Ultimately, in order to attain enlightenment, we must exhaust all our karma, both good and bad, not merely collect as much good karma as we can and get rid of the bad. Karma is by nature conditioning, and since all our activities are conditioned by karma, they can only be a direct contradiction to our independence. Therefore, it is not possible for any of us to be truly independent.
The point of thinking about cause and effect before we start to practice each day is not merely to gather knowledge about karma’s complex functions and systems, but to remind ourselves that we have no control over anything at all.

Dzongsar Khyentse Rinpoche
from the book Not for Happiness: A Guide to the So-Called Preliminary Practices
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